Обзоры конференций и рекомендации по применению JaFron

38th Vicenza Course Jafron Webinar Academic Perspectives

Academic Perspective 19.11.2020

Academic Perspective 22.10.2020

Academic Perspective 29.09.20

Academic Perspectives AKI CRRT 2020

Academic Perspectives. Webinar of Live Support Alive

Academic Perspectives. Europe COVID-19 23.06.20

Academic Perspectives. Russian Symposium 30.07.20

Academic Perspective. Hemoadsorption – A Novel Organ Support Therapy for Critical Diseases 17.09.2020

Academic Perspective. Hemoperfusion for COVID-19 patients with AKI and or respiratory failure  Experience from Europe

Clinical Cases Collection from Jafron Biomedical Co., Ltd, Zhuhai, China

Clinical Reference for Adsorption therapy from Prof. Ronco

Cytokine adsorption devices for treating respiratory failure in people with COVID-19

Discussion and Q&A  19.11.2020

Experience of coronavirus from China

FAQ for hemoperfusion application and operation in COVID-19pandemic fighting

International Expert Opinions and Experience from China

Jafron Oversea Clinical Cases Collection

Jafron HA330 HA380 Hemoperfusion Cartridge for COVID-19 Cytokine Storm Management

Jafron HA330 HA380 Hemoperfusion Cartridge for COVID-19 with Acute Kidney Injure

Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases. WHO

Montin D. P. et al. Biocompatibility and cytotoxic evaluation of new sorbent cartridges for blood hemoperfusion Blood purification. – 2018. – Т. 46. – №. 3. – С. 187-195.

Novel Coronavirus Infection with Liver Failure

Q&A of Internal Webinar 25.06.2020

Научные публикации

Соколов А. А. и др. Методы экстракорпоральной гемокоррекции в комплексном лечении новой коронавирусной инфекции: обзор возможностей //Вестник анестезиологии и реаниматологии. – 2020. – Т. 17. – №. 4. – С. 31-40.

Azzabou N., Hogrel J. Y., Carlier P. G. NMR based biomarkers to study age-related changes in the human quadriceps //Experimental gerontology. – 2015. – Т. 70. – С. 54-60.

Banagozar Mohammadi A, Zaare Nahandi M, Mohammadian S. The Successful Treatment of High Lethal Dose Paraquat Poisoning With Hemoperfusion. International Journal of Medical Toxicology and Forensic Medicine. 2020

Bo L. Therapeutic efficacies of different hemoperfusion frequencies in patients with organophosphate poisoning //Eur Rev Med Pharmacol Sci. – 2014. – Т. 18. – №. 22. – С. 3521-3523.

Chen, J., Huang, J., Chen, Y., Lu, Y., & Li, L. (2012). A clinical study on the treatment of severe hepatitis by a combined artificial liver. Hepato-gastroenterology, 59(119), 2273-2275.

Cheng W, Luo Y, Wang H, Qin X, Liu X, Fu Y, Ronco C. Survival Outcomes of Hemoperfusion and Hemodialysis versus Hemodialysis in Patients with End-Stage Renal Disease: A Systematic Review and Meta-Analysis. Blood Purif. 2021 May 10:1-13.

Li M. et al. Clinical observation on the treatment of acute liver failure by combined non-biological artificial liver //Experimental and therapeutic medicine. – 2016. – Т. 12. – №. 6. – С. 3873-3876.

Chen J. et al. A clinical study on the treatment of severe hepatitis by a combined artificial liver //Hepato-gastroenterology. – 2012. – Т. 59. – №. 119. – С. 2273-2275

Chu L. et al. Clinical effects of hemoperfusion combined with pulse high-volume hemofiltration on septic shock —Medicine. – 2020. – Т. 99. – №. 9. – С. e19058.

Clark W. R. et al. Extracorporeal sorbent technologies: basic concepts and clinical application //Current Perspectives in Kidney Diseases. – Karger Publishers, 2017. – Т. 190. – С. 43-57.

Cytokine adsorption devices for treating respiratory failure in people with COVID-19.

Dastan F. et al. Continues renal replacement therapy (CRRT) with disposable hemoperfusion cartridge- A promising option for severe COVID-19 —Journal of Global Antimicrobial Resistance. – 2020.

Dastan F. et al. Continues renal replacement therapy (CRRT) with disposable hemoperfusion cartridge: a promising option for severe COVID-19 //Journal of global antimicrobial resistance. – 2020. – Т. 21. – С. 340-341.

Dr. Liang Yu «Haemoperfusion: a Promising Extracorporeal Blood Purification therapy in improving the ICU outcomes of critically ill patients with COVID-19»

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China- 2020-1-29

Gao X. F. et al. Effect of hybrid blood purification treatment on secondary hyperparathyroidism for maintenance hemodialysis patients //Blood purification. – 2018. – Т. 46. – №. 1. – С. 19-26.

Guo Jing, Xia He, Wang Shuting et al. The Artificial-Liver Blood-Purification System Can Effectively Improve Hypercytokinemia for COVID-19

Gu Y. H. et al. Additional hemoperfusion is associated with improved overall survival and self-reported sleep disturbance in patients on hemodialysis —The International journal of artificial organs. – 2019. – Т. 42. – №. 7. – С. 347-353.

Haidari Z. et al. Intraoperative hemoadsorption in patients with native mitral valve infective endocarditis //The Annals of Thoracic Surgery. – 2020.

He H., Xie Y. Effect of Different Hemodialysis Methods on Microbiota in Uremic Patients —BioMed Research International. – 2020. – Т. 2020.

Hifumi T. et al. Venomous snake bites: clinical diagnosis and treatment //Journal of intensive care. – 2015. – Т. 3. – №. 1. – С. 16.

Huang C. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China The Lancet. – 2020.

Huang C. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China //The lancet. – 2020. – Т. 395. – №. 10223. – С. 497-506.

Huang J. et al. Acute abrin poisoning treated with continuous renal replacement therapy and hemoperfusion successfully: A case report //Medicine. – 2017. – Т. 96. – №. 27.

Huang Z. et al. Effect on Extrapulmonary Sepsis‐Induced Acute Lung Injury by Hemoperfusion With Neutral Microporous Resin Column //Therapeutic Apheresis and Dialysis. – 2013. – Т. 17. – №. 4. – С. 454-461.

Huang Zhao Wang Sirong, ji-yun liu. Blood perfusion treatment of sepsis the removal of inflammatory markers in patients with acute kidney injury and renal protection [J]. Chinese journal of emergency medicine, 2011, 20 (1) : 60-64.

Hu L. et al. Clearance rate and BP-ANN model in paraquat poisoned patients treated with hemoperfusion //BioMed research international. – 2015. – Т. 2015.

Huu D. N. et al. A Combination of Hemodialysis with Hemoperfusion Helped to Reduce the Cardiovascular-Related Mortality Rate after a 3-Year Follow-Up: A Pilot Study in Vietnam //Blood purification. – С. 1-8.

Jiang S. et al. Clinical efficacy of intravenous infusion of atropine with micropump in combination with hemoperfusion on organophosphorus poisoning //Saudi Journal of Biological Sciences. – 2019. – Т. 26. – №. 8. – С. 2018-2021.

Li C., Xu N., Xu T. Therapeutic Effects of Hemoperfusion Combined with High Volume Hemofiltration on Acute Respiratory Distress Syndrome Short Title_ Treatment of ARDS __Revista Argentina de Clínica Psicológica. – 2020. – Т. 29. – №. 3.

Li L. et al. Transjugular Intrahepatic Portosystemic Shunt Combined with Haemoperfusion in an End-stage Renal Disease Patient with Liver Cirrhosis-related Refractory

Li M. et al. Combined use of non-biological artificial liver treatments for patients with acute liver failure complicated by multiple organ dysfunction syndrome //World Journal of Emergency Medicine. – 2014. – Т. 5. – №. 3. – С. 214.

Li M. et al. Efficacy of various combined blood purification techniques for treating patients with non-viral acute liver failure //Cell biochemistry and biophysics. – 2014. – Т. 68. – №. 3. – С. 571-575.

Li P. et al. A non-bioartificial liver support system combined with transplantation in HBV-related acute-on-chronic liver failure ::Scientific reports. – 2021. – Т. 11. – №. 1. – С. 1-9

Liu S. et al. High‐volume continuous venovenous hemodiafiltration plus resin hemoperfusion improves severe metformin‐associated toxicity //Journal of diabetes investigation. – 2018. – Т. 9. – №. 4. – С. 975-978.

Liu S. et al. HA280 immunoadsorption, an alternative treatment for neuromyelitis optica spectrum disorders? —Multiple sclerosis and related disorders. – 2020. – Т. 37. – С. 101480.

Li W. H. et al. Curative effect of neutral macroporous resin hemoperfusion on treating hemodialysis patients with refractory uremic pruritus //Medicine. – 2017. – Т. 96. – №. 12.

Lina Chen, Zheng Wang, Songhui Zhai, et. The Effects of hemoperfusion in the treatment of childhood Henoch — Sch nlein purpura nephritis. Int J Artif Organs 2013;36 (7) : 489-497.

Li W. H. et al. Curative effect of neutral macroporous resin hemoperfusion on treating hemodialysis patients with refractory uremic pruritus //Medicine. – 2017. – Т. 96. – №. 12.

Mao Huljuan, Yu Shu, Zhang Bo, et al. Effects of coupled plasma filtration adsorption on serum cytokines in patients with multiple organ dysfunction syndromes [J]. Chinese Journal of Blood Unification, 2009 (8)2: 70-75.

Maoujoud O. et al. Coronavirus Disease 19 Pandemic and Extracorporeal Therapies in Intensive Care__ Bis Peccare in Bello Non Licet_ __Blood purification. – 2020. – С. 1-2.

Nadim M. K. et al. COVID-19-associated acute kidney injury/ consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup //Nature Reviews Nephrology. – 2020. – С. 1-18.

Nalesso F. et al. A Continuous Renal Replacement Therapy Protocol for Patients with Acute Kidney Injury in Intensive Care Unit with COVID-19//Journal of Clinical Medicine. – 2020. – Т. 9. – №. 5. – С. 1529

Nogaibayeva A. et al. SAT-052 Combined Extracorporeal Hemocorrection Early Applying in Sepsis and Severe Acute Kidney Injury Therapy __Kidney International Reports. – 2020. – Т. 5. – №. 3. – С. S22-S23.


Raine A., Cordonnier D., Ritz E. Effect of hematodialysis plus hemoperfusion on insulin resistance and nutritional status of patients with end-stage diabetic nephropathy //J Int Transl Med. – 2015. – Т. 51. – С. 180-4.

Ramirez-Guerrero G, Torres Cifuentes V, Baghetti Hernandez R, Villagran Cortes F, Rojas Doll S, Oliva Alarcon R, Lucero Cordova C, Flores Fernandez P, Garay Coloma O_ Early Cytokine Removal in Critical COVID-19 Patients with Extracorporeal Therapies

Romina A. Danguilan «Hemoperfusion: An Innovative Adsorption Technology for Multi Organ Failure»

Ronco C. et al. Extracorporeal Blood Purification and Organ Support in the Critically Ill Patient during COVID-19 Pandemic_ Expert Review and Recommendation __Blood Purification. – 2020. – С. 1-11.

Ronco C. et al. Interpreting the mechanisms of continuous renal replacement therapy in sepsis: the peak concentration hypothesis //Artificial organs. – 2003. – Т. 27. – №. 9. – С. 792-801.

Ronco C., Reis T., De Rosa S. Coronavirus epidemic and extracorporeal therapies in intensive care: si vis pacem para bellum //Blood Purification. – 2020. – Т. 49. – №. 3. – С. 255-258.

Ronco C., Reis T., Husain-Syed F. Management of acute kidney injury in patients with COVID-19 __The Lancet Respiratory Medicine. – 2020.

Ronco C., Navalesi P., Vincent J. L. Coronavirus epidemic- preparing for extracorporeal organ support in intensive care __The Lancet Respiratory Medicine. – 2020. – Т. 8. – №. 3. – С. 240-241

Ronco C., Reis T. Kidney involvement in COVID-19 and rationale for extracorporeal therapies Nature Reviews Nephrology. – 2020. – С. 1-3

Ronco C., Reis T., De Rosa S. Coronavirus epidemic and extracorporeal therapies in intensive care/ si vis pacem para bellum //Blood Purification. – 2020. – Т. 49. – №. 3. – С. 255-258.

Safari S. et al. Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Severe COVID-19 patients; a Narrative Review __Archives of academic emergency medicine. – 2020. – Т. 8. – №. 1.

Saparov А.I., Tobylbayeva Z.S., et al. A Case of Successful Application of HA 330 System for Treatment of Sepsis in a 6-month Old Hematological Patient//National Research Center for Maternal and Child Health, Corporate Fund University Medical Center (CF UMC), Turan Ave 32, Nur- Sultan, Kazakhstan//International Journal of Medical Science and Health Research Vol. 4, No. 04; 2020

Shun Jie Chen, Geng Ru Jiang, Jiang Ping Shan, et al, The Combination of maintenance hemodialysis with hemoperfusion: A safe and effective model of artificial kidney. The International Jurnal of artificial Organs, 2011 (4) : 339-347.

Shu Li, Haina Gan, Jinwei Chen, Suqing Xu, Jinfeng Du, Guanhui Ling The short-term efficacy and safety of treatment of HA280 immunoadsorption column in the polymyositis

Si X. et al. Clinical evaluation of high-volume hemofiltration with hemoperfusion followed by intermittent hemodialysis in the treatment of acute wasp stings complicated by multiple organ dysfunction syndrome //PloS one. – 2015. – Т. 10. – №. 7.

Song F. et al. Modified poisoning severity score for early prognostic evaluation in acute paraquat poisoning //Medical Journal of Chinese People’s Liberation Army. – 2018. – Т. 43. – №. 4. – С. 337-340.

Sun S. et al. High-volume hemofiltration plus hemoperfusion for hyperlipidemic severe acute pancreatitis: a controlled pilot study //Annals of Saudi medicine. – 2015. – Т. 35. – №. 5. – С. 352-358.

Sun, S., He, L., Bai, M., Liu, H., Li, Y., Li, L., Huang, C. (2015). High-volume hemofiltration plus hemoperfusion for hyperlipidemic severe acute pancreatitis: a controlled pilot study. Annals of Saudi medicine, 35(5), 352-358.

Tang, X. M., Zou, Z. Y., Zhao, X. D., Chen, X. L., Zhang, Y., & Li, Q. (2012). DNA immunoadsorption for childhood-onset systemic lupus erythematosus.

Topic Exploration Report. Cytokine adsorbers for the treatment of cytokine storm in people with severe coronavirus infection

Jiang J. K. et al. Early changes of peripheral blood lymphocyte subpopulations in patients with occupational 2, 4-dinitrophenol poisoning //Biomedical and Environmental Sciences. – 2016. – Т. 29. – №. 12. – С. 909-914.


Juneja D. et al. Severe suicidal digoxin toxicity managed with resin hemoperfusion: A case report //Indian journal of critical care medicine: peer-reviewed, official publication of Indian Society of Critical Care Medicine. – 2012. – Т. 16. – №. 4. – С. 231.

Kellum J. A., Bellomo R., Ronco C. (ed.). Continuous renal replacement therapy. – Oxford University Press, 2016.

Kjaergard L. L. et al. Artificial and bioartificial support systems for acute and acute-on-chronic liver failure: a systematic review //Jama. – 2003. – Т. 289. – №. 2. – С. 217-222.

Krenn C. G., Steltzer H. Hämoadsorption zur Blutreinigung–Unvergleichbarkeit der klinisch angebotenen Verfahren //Medizinische Klinik-Intensivmedizin und Notfallmedizin. – 2020. – С. 1-5.

Le T. Q., Be T. H., Pham D. Retrospective observational case-control study comparing the effectiveness of activated charcoal and resin hemoperfusion on treatment of acute paraquat poisoning //PLoS One. – 2012. – Т. 7. – №. 10.

Li A. et al. Early stage blood purification for paraquat poisoning: a multicenter retrospective study //Blood purification. – 2016. – Т. 42. – №. 2. – С. 93-99.

Tang Yi, Zhang Ling, Ying Yingying, et al. Hemoperfusion plus contingous veno-venous hemofiltration for patients with sepsis and acute kidney injury [J]. Medical Journal of West China, 2012, 24(2): 233-235, 238.

UK NICE. Cytokine adsorption devices for treating respiratory failure in people with COVID-19

Wang Mei, 72 cases of pediatric allergic purpura nursing of hemoperfusion therapy [J]. Nursing Practice and Research, 2012, 9 (7): 64-65.

Wang Q., Hu Z. Successful recovery of severe COVID-19 with cytokine storm treating with extracorporeal blood purification __International Journal of Infectious Diseases. – 2020.

Wang, Y. T., Fu, J. J., Li, X. L., Li, Y. R., Li, C. F., & Zhou, C. Y. (2016). Effects of hemodialysis and hemoperfusion on inflammatory factors and nuclear transcription factors in peripheral blood cell of multiple organ dysfunction syndrome. Eur Rev Med Pharmacol Sci, 20(4), 745-50.

Selected Abstracts from the 38th Vicenza Course on AKI & CRRT

Shadvar K, Tagizadiyeh A, Gamari A, A, Soleimanpour H, Mahmoodpoor A: Hemoperfusion as a Potential Treatment for Critically Ill COVID-19 Patients with Cytokine Storm. Blood Purif 2020

Xia Q. et al. A single-center experience of non-bioartificial liver support systems among Chinese patients with liver failure //The International journal of artificial organs. – 2014. – Т. 37. – №. 6. – С. 442-454.

Xu K, Cai H, Shen Y, et al. [Management of corona virus disease-19 (COVID-19)- the Zhejiang experience

Xu X. et al. Effect of HA330 resin-directed hemoadsorption on a porcine acute respiratory distress syndrome model //Annals of intensive care. – 2017. – Т. 7. – №. 1. – С. 84.

Ye Q., Wang B., Mao J. The pathogenesis and treatment of theCytokine Storm’in COVID-19 //Journal of infection. – 2020. – Т. 80. – №. 6. – С. 607-613.

Zhang J. et al. Comparison of combined blood purification techniques in treatment of dialysis patients with uraemic pruritus //Int J Clin Exp Med. – 2016. – Т. 9. – №. 5. – С. 8563-8568.

Zhang Z. Y. et al. Combination of Multiple Hemodialysis Modes: Better Treatment Options for Patients Under Maintenance Hemodialysis ::Therapeutics and Clinical Risk Management. – 2021. – Т. 17. – С. 127

Zhao Huang Si Rong, Wang, Wei Su, et al. The Removal of Humoral Mediators and the Effect on the Survival of Septic Patients by Hemoperfusion with Neutral Microporous Resin Column [J]. Journal of Therapeutic Apheresis and Dialysis, 2010, 14 (6) : 596-602.

覃德芹周锐王辉. 2011-2015 年安徽省宣城市农村地区百草枯中毒流行病学特征及对居民期望寿命的影响 //疾病监测. – 2017. – Т. 32. – №. 2. – С. 157-161.